SS-31 (Elamipretide) 10 mg

Product Overview

SS-31, also known as Elamipretide, MTP-131, or Bendavia, is a synthetic mitochondria-targeting tetrapeptide developed to investigate mitochondrial function and cellular energy production. Unlike many research peptides that interact with cell-surface receptors, SS-31 selectively accumulates within the inner mitochondrial membrane, where it binds to cardiolipin, a phospholipid essential for maintaining normal mitochondrial structure and function. (PMC)

This research-grade 10 mg lyophilized SS-31 is manufactured for laboratory investigations involving mitochondrial biology, oxidative stress, cellular energy metabolism, and age-related cellular dysfunction.

Origin

SS-31 was developed by researchers Dr. Hazel Szeto and Dr. Peter Schiller as part of the Szeto-Schiller (SS) family of mitochondria-targeting peptides. The peptide was specifically engineered to penetrate cells rapidly and localize within mitochondria without relying on membrane potential, making it a unique tool for mitochondrial research. (The Peptide Catalog)

Mechanism of Action

SS-31 is designed to selectively bind cardiolipin within the inner mitochondrial membrane. Research suggests this interaction may help stabilize mitochondrial structure, improve electron transport chain efficiency, reduce reactive oxygen species (ROS), and support ATP production during cellular stress. These properties have made SS-31 one of the most extensively studied mitochondria-targeted peptides in preclinical research. (PMC)

Areas of Research

Current laboratory investigations explore SS-31 in models involving:

Mitochondrial dysfunction

Cellular energy metabolism

ATP production

Oxidative stress

Healthy aging research

Skeletal muscle biology

Cardiovascular research

Kidney biology

Neuroprotection

Exercise physiology and recovery

Features

10 mg lyophilized SS-31 (Elamipretide)

High-purity synthetic tetrapeptide

Mitochondria-targeting research compound

Stable freeze-dried formulation

Suitable for laboratory and analytical applications

Batch-tested for identity and purity

Potential Research Benefits

Scientific investigations have explored SS-31 for its potential role in:

Supporting mitochondrial integrity

Improving mitochondrial energy production

Reducing oxidative stress in cellular models

Enhancing ATP synthesis efficiency

Protecting cells during metabolic stress

Supporting healthy cellular aging research

Investigating muscle and tissue resilience

Studying mitochondrial-related disorders

Observed effects vary depending on the experimental model and should not be interpreted as established clinical outcomes. SS-31 remains an investigational compound undergoing continued scientific evaluation. (PMC)

Storage

Store the lyophilized peptide refrigerated or frozen according to laboratory guidelines. Following reconstitution, handle and store the material in accordance with the manufacturer’s recommendations to maintain stability and research integrity.

Research Use Only

This product is supplied strictly for laboratory, analytical, and scientific research purposes only.

It is not intended for human or veterinary use and is not approved to diagnose, treat, cure, or prevent any disease. This material should only be handled by qualified professionals operating in appropriate research environments.